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Adequan® Canine is the only FDA-approved, injectable, disease-modifying osteoarthritis drug (DMOAD) for dogs in the US that inhibits enzymes that break down cartilage, so joint damage is reduced. Treatment with Adequan® Canine travels to the joint quickly ‐ within 2 hours ‐ and it stays in the joint for three days. Adequan® Canine is administered twice weekly for up to four weeks with a maximum of eight injections. You should see signs of improvement within a month.
Adequan® Canine is recommended for intramuscular injection for the control of signs associated with non-infectious degenerative and/or traumatic arthritis of canine synovial joints.
Adequan requires a prescription from your veterinarian. A syringe is needed, but not included in the package. Please see 3cc (3ml) luer slip syringe with 3/4" 25 g Needle.
Dogs
Do not give this medication to breeding, pregnant, or lactating animals. Talk to your veterinarian before using in dogs with kidney or liver disease, or bleeding disorders. Not for use in dogs who are hypersensitive to Adequan or who have known or suspected bleeding disorders.
Adequan
Polysulfated Glycosaminoglycan (PSGAG) Solution
Give the missed dose as soon as possible. However, if it is almost time for the next regularly scheduled dose, skip the missed dose and give the next one as directed. Do not give a double dose of the medication.
Side effects in clinical studies (pain at injection site, diarrhea and abnormal bleeding) were mild, transient and self-limiting. In post approval experience, death has been reported in some cases; vomiting, anorexia, depression/ lethargy and diarrhea have also been reported. Contact your veterinarian if you notice these symptoms.
Store Adequan at room temperature (64º-77º F). Keep this medication out of the reach of children and pets.
Directions:
Give this medication exactly as directed by your veterinarian. Adequan is given by intramuscular (IM, into the muscle) injection.
Dosage:
| Pet | Weight | Dosage |
|---|---|---|
| Dogs: | All weights | Inject 2mg per lb given only by intramuscular (IM) injection twice a week for up to 4 weeks (a maximum of 8 injections) |
| Cats: | X | X |
| Horses: | X |
Adequan (for Dogs):
| Active Ingredients | Amount |
|---|---|
| Polysulfated Glycosaminoglycan | 100 mg |
| benzyl alcohol (a preservative) | 0.9% v/v |
| water | |
Other Ingredients: | |
Excel Enteric Coated Aspirin provides temporary pain relief, making this an ideal medication for dogs with arthritis and related joint problems. This aspirin also helps to reduce inflammation and joint stiffness. Excel Enteric Coated Aspirin is not for use in cats.
Meloxicam is a nonsteroidal anti-inflammatory (NSAID) prescription medication used to reduce pain, inflammation, and stiffness as a result of acute and chronic musculoskeletal disorders such as osteoarthritis. Meloxicam requires a prescription from your veterinarian, and is sold per tablet.
Onsior for Cats is a non-steroidal anti-inflammatory drug (NSAID) that relieves pain and reduces inflammation associated with orthopedic and soft tissue surgery. The small, yeast-flavored tablets are favored by cats and are easy to administer. Onsior is available in a 6mg 3-pack blister packet. Onsior requires a prescription from your veterinarian.
Azathioprine is a prescription medication used in dogs and cats for the treatment of autoimmune diseases. Azathioprine is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe this medication for dogs and cats. Azathioprine requires a prescription from your veterinarian, and is sold per tablet.
Novox is a generic equivalent for Rimadyl (carprofen) caplets. It's a non-steroidal anti-inflammatory (NSAID) used to treat pain and inflammation due to arthritis and other joint diseases, including hip dysplasia. It's also used to reduce fever. Novox requires a prescription from your veterinarian.
Deramaxx is used in dogs to control pain and inflammation. Its particularly effective against osteoarthritis, a degenerative disease that affects your dogs joints. It is available as beef-flavored, scored, chewable tablets. Deramaxx requires a prescription from your veterinarian.
Metacam (meloxicam) is a non-steroidal anti-inflammatory (NSAID) medication used to treat pain and inflammation in dogs. It also has other benefits, including fever reduction. Metacam for Dogs requires a prescription from your veterinarian. Metacam Pain Medication for Dogs
The 3cc (3ml) Luer-Slip syringe with 3/4" 22 g Needle is a syringe that works with Adequan, which controls the symptoms of arthritis, or Percorten-V, which controls Addison's Disease. The syringe comes with a needle and allows up to 3 cc (3 ml) of medication for your pet.
Galliprant (Grapiprant) Flavored Tablets are for the control of pain and inflammation associated with osteoarthritis in dogs.
Carprovet Flavored Tablets (compares to Rimadyl) are used for the relief of pain and inflammation associated with osteoarthritis and for the control of postoperative pain associated with soft tissue and orthopedic surgeries in dogs.
Adequan® Equine I.M. (polysulfated glycosaminoglycan) is the only FDA-approved treatment proven to relieve symptoms of non-infectious degenerative osteoarthritis, to stimulate cartilage repair and reverse the joint disease process.
Gabapentin is a medication for dogs and cats for the treatment of seizures. It is also used to help with chronic pain. Although Gabapentin is not FDA-approved for use in veterinary medicine, it is a commonly accepted practice for veterinarians to prescribe this medication.

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