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Simplicef is a cephalosporin antibiotic used to treat skin infections (wounds and abscesses) caused by susceptible strains of bacteria. It is administered once a day and requires a prescription from your veterinarian. It is sold per tablet. Its long half-life allows for once-daily dosing, which may result in increased compliance and better clinical outcomes.
Dogs
Dogs with known hypersensitivity to penicillin or cephalosporins should not be given simplicef. Do not use in dogs with known allergy to penicillins or cephalosporins. The safety of cefpodoxime proxetil in dogs used for breeding, pregnant dogs, or lactating bitches has not been demonstrated.
Simplicef (Pfizer Animal Health)
Cefpodoxime proxetil
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give your pet two doses at once.
Mild nausea, diarrhea, or yeast infection may be more likely to occur. Continue to give Simplicef and notify your veterinarian if these symptoms occur.
Should be stored in a cool dry place.
Give this medication as directed by your veterinarian. Simplicef should be given with food to increase absorption in the body. Keep plenty of water available for your pet to drink. Give all of the Simplicef even if your pet appears to be better. Symptoms may improve before the infection is completely treated.
| Dogs: | |
Weight | Dosage |
| All weights | Give this medication exactly as directed by your veterinarian. The usual dose of Simplicef in dogs is 2.3-4.5mg/pound, given by mouth, once a day for 5 to 7 days or 2 to 3 days beyond the cessation of clinical signs, up to a maximum of 28 days. |
| Cats |
| Do not use! |
| Horses |
| Do not use! |
| Simplicef 100 mg: | |
Ingredient | Strength |
| Cefpodoxime proxetil | 100 mg |
| Simplicef 200 mg: | |
Ingredient | Strength |
| Cefpodoxime proxetil | 200 mg |
Clavamox is a broad spectrum antibiotic, a combination of amoxicillin and clavulanic Acid, used for infections caused by bacteria. Clavamox requires a prescription from your veterinarian, and is sold by the tablet. It is also available as oral drops.
Clindamycin Oral Liquid Antibiotic is an antibiotic used to treat soft tissue infections, dental infections, and bone infections caused by susceptible strains of bacteria. Clindamycin Oral Liquid Antibiotic requires a prescription from your veterinarian.
Metronidazole is an antibiotic and antiprotozoal medication used to treat various conditions such as inflammatory bowel disease, nonspecific diarrheal disorders, infections caused by Giardia (a cause of diarrhea), and periodontal disease. Metronidazole requires a prescription from your veterinarian, and is sold by the tablet.
Cefpodoxime proxetil is an oral cephalosporin antibiotic used to treat bacterial infections of the skin, such as wounds, abscesses as well as bladder and respiratory infections in dogs and skin and soft tissue infections in cats. Cefpodoxime proxetil is not FDA approved for use in veterinary medicine; however, it is a commonly accepted practice for veterinarians to prescribe.
Mupirocin is an antibiotic ointment used for the treatment of canine bacterial infections of the skin. These skin infections can include superficial pyoderma, caused by susceptible strains of Staphylococcus aureus and Staphylococcus intermedius. Mupirocin requires a prescription from your veterinarian.
Derma-Vet Ointment is an antimicrobial, antifungal and corticosteroid formulation in an easy-to-apply topical gel base used in the treatment of skin disorders characterized by inflammation and dry or exudative dermatitis caused by bacterial or candidal infections.
B.N.P. with Hydrocortisone Triple Antibiotic Ophthalmic Ointment is a sterile ointment that is used to topically treat eye infections that are accompanied by inflammation. B.N.P. with Hydrocortisone Triple Antibiotic Ophthalmic Ointment requires a prescription from your veterinarian.
Marboquin are used to treat marbofloxacin-susceptible infections in cats and dogs.

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